Quantification of piroxicam and 5′-hydroxypiroxicam in human plasma and saliva using liquid chromatography-tandem mass spectrometry following oral administration
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- 作者：Adriana Maria Calvoa ; Gabriel Mulinari Santosa ; Thiago José ; Dioní ; sioa ; Maria Paula Marquesb ; Daniel Thomas Brozoskia ; Vera Lú ; cia Lanchoteb ; Maria Helena Raposo Fernandesc ; Flá ; vio Augusto Cardoso Fariaa ; Carlos Ferreira Santosa ; cfsantos@fob.usp.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：LC&ndash ; MS/MS ; Piroxicam ; 5&prime ; -Hydroxypiroxicam ; Plasma ; Saliva
- 刊名：Journal of Pharmaceutical and Biomedical Analysis
- 出版年：2016
- 出版时间：20 February 2016
- 年：2016
- 卷：120
- 期：Complete
- 页码：212-220
- 全文大小：1206 K
文摘
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Human plasma and saliva samples used for pharmacokinetics studies.
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Validation methods of piroxicam and 5′-hydroxypiroxicam extraction in plasma and saliva.
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Piroxicam and 5′-hydroxypiroxicam in saliva samples can be quantified using LC–MS/MS.