Continuous bacteriocin production with high cell density bioreactors
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- 作者：Bhugaloo-Vial ; Parwin ; Grajek ; Wlodzimierz ; Dousset ; Xavier ; Boyaval ; Patrick
- 关键词：Bacteriocin ; Carnobacterium ; continuous fermentation ; immobilized cells ; membrane bioreactor
- 刊名：Enzyme and Microbial Technology
- 出版年：1997
- 出版时间：November 1, 1997
- 年：1997
- 卷：21
- 期：6
- 页码：450-457
- 全文大小：725 K
文摘
The production of divercin, a bacteriocin active against Listeria, by whole cells of Carnobacterium divergens V41 was investigated by three means: continuous cultivation with free cells; with cells immobilized in calcium-alginate beads packed in a plug-flow bioreactor, and with a membrane bioreactor. The productivity and bacteriocin concentrations of the systems were compared. Immobilized cells presented the best performances with more than 105 AU l−1 h−1 which can be compared to the 2.8 × 103 AU l−1 h−1 of the batch system. The membrane bioreactor failed to be efficient for low transmission of the bacteriocin through the membranes tested.