Fight, Flight, or Freeze? The Answer May Depend on Your Sex

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• 作者：Carolyn E. Jonesp>1p> ; Marie-H. Monfilsp>1p>p> ; p>p>marie.monfils@utexas.edu" class="auth_mail" title="E-mail the corresponding authorp>
• 关键词：females ; sex differences ; fear conditioning ; escape
• 刊名：Trends in Neurosciences
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：39
• 期：2
• 页码：51-53
• 全文大小：658 K

文摘

Pavlovian fear conditioning is one of the most common and well-understood methods for studying fear learning. However, research is predominantly performed in males. Recently, in a classical Pavlovian fear conditioning paradigm, Gruene and colleagues described an active conditioned fear response (‘darting’) prevalent in female rats that better maintain an extinction memory.