Two-cohort study including 750 patients to scrutinize the actual impact of prophylactic gentamicin/penicillin G or cefuroxime on ESBL/AmpC/CPE carrier status, which is poorly investigated.
Low carriage rate of ESBL/AmpC/CPE in the two included patient cohorts prior to surgery was detected.
No significant impact on the fecal carriage of ESBL/AmpC-producing Enterobacteriaceae by use of gentamicin/penicillin G or cefuroxime was detected 2-days post surgery.
In one cohort, carriage was significantly associated with previous hospital admission and antimicrobial treatment, and men had a greater risk of carriage than women.