Functional characterization of solute carrier (SLC) 26/sulfate permease (SulP) proteins in membrane mimetic systems
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- 作者：Lakshmi Srinivasana ; Lakshmi.Srinivasan@biophys.mpg.de" class="auth_mail" title="E-mail the corresponding author ; Tonie Luise Baarsa ; Tonie.Baars@biophys.mpg.de" class="auth_mail" title="E-mail the corresponding author ; Klaus Fendlerb ; Klaus.Fendler@biophys.mpg.de" class="auth_mail" title="E-mail the corresponding author ; Hartmut Michela ; Hartmut.Michel@biophys.mpg.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Solute carrier (SLC)26 ; Bicarbonate transport by sulfate permease ; Membrane mimetics ; Fluorescence quench studies in nanodiscs ; Solid supported membrane-based electrophysiology ; Transport assays in proteoliposomes
- 刊名：Biochimica et Biophysica Acta (BBA)-Biomembranes
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：1858
- 期：4
- 页码：698-705
- 全文大小：804 K
文摘
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SLC 26 family transporters may be multifunctional and may transport different anions depending on the conditions.
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Electrogenic, chloride dependent transport events were recorded in liposomes.
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Fumarate is a low-affinity substrate for StmYchM/DauA.
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20">Bicarbonate is transported with a high flux at alkaline pH