One-pot multicomponent synthesis of 2,3-dihydropyrans: new access to furanose–pyranose 1,3-C–C-linked-disaccharides

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• 作者：Daniele Castagnolo ; Lorenzo Botta ; Maurizio Botta
• 关键词：Enyne metathesis ; Hetero-Diels– ; Alder ; Multicomponent reaction ; Dihydropyrans ; Disaccharide
• 刊名：Tetrahedron Letters
• 出版年：2009
• 出版时间：8 April 2009
• 年：2009
• 卷：50
• 期：14
• 页码：1526-1528
• 全文大小：437 K

文摘

An efficient synthesis of 2,3-dihydropyrans from different terminal alkynes was developed. The 2,3-dihydropyrans were obtained in a few minutes through a microwave-assisted multicomponent enyne cross-metathesis/hetero-Diels–Alder reaction. Starting from C-ethynyl-ribofuranose, a new multicomponent approach to furanose–pyranose 1,3-C–C-linked disaccharides was also developed.