Patterns of failure after reirradiation with intensity-modulated radiation therapy and the competing risk of out-of-field recurrences
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- 作者：Danielle N. Margalit ; MD MPHa ; dmargalit@lroc.harvard.edu" class="auth_mail" title="E-mail the corresponding author ; Bhupendra Rawal ; MSb ; Paul J. Catalano ; ScDb ; Robert I. Haddad ; MDc ; Laura A. Goguen ; MDd ; Donald J. Annino ; MD DMDd ; Sewanti A. Limaye ; MD MSc ; Jochen H. Lorch ; MD MSc ; Annie W. Lavignea ; Jonathan D. Schoenfeld ; MD MPHa ; David J. Sher ; MDa ; Roy B. Tishler ; MD PhDa
- 关键词：Head and neck cancer ; Oral cancer ; Recurrent head and neck cancer ; Reirradiation ; Intensity modulated radiation therapy ; Patterns of failure ; Patterns of recurrence ; Recurrent and metastatic ; Squamous cell carcinoma ; Radiation therapy ; Chemotherapy ; Surgical salvage ; Local regional recurrence ; Distant metastases
- 刊名：Oral Oncology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：61
- 期：Complete
- 页码：19-26
- 全文大小：1131 K
文摘
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Patterns of failure differ when reirradiation is definitive versus postoperative.
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After definitive reirradiation, in-field failure is the most common local-regional failure.
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After postoperative reirradiation, out-of-field failure is more common than in-field.
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Concurrent distant failure occurs frequently with local-regional recurrence.