Proline-arginine rich (PR-39) cathelicidin: Structure, expression and functional implication in intestinal health
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- 作者：Ravi Holania ; Chaitanya Shahb ; Qahir Hajib ; G. Douglas Inglisc ; Richard R.E. Uwierad ; Eduardo R. Coboa ; ecobo@ucalgary.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cathelicidin ; Proline-arginine-peptide ; PR-39 ; Pig ; Intestine ; Infectious disease ; Neutrophil ; Antimicrobial ; Immunemodulator
- 刊名：Comparative Immunology, Microbiology and Infectious Diseases
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：49
- 期：Complete
- 页码：95-101
- 全文大小：1197 K
文摘
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Cathelicidin proline-arginine-39 (PR-39) is key in porcine innate immuity.
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PR-39 has immunomodulatory, wound healing, anti-apoptotic, and pro-angiogenic roles.
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PR-39 may evolve as therapeutic alternative for infectious enterocolitis in pigs.