Multiple Ways to Manage Portal Thrombosis During Liver Transplantation: Surgical Techniques and Outcomes

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• 作者：G. D'Amico ; G. Tarantino ; M. Spaggiari ; R. Ballarin ; V. Serra ; G. Rumpianesi ; R. Montalti ; N. De Ruvo ; N. Cautero ; B. Begliomini ; G.E. Gerunda ; F. Di Benedetto
• 刊名：Transplantation Proceedings
• 出版年：2013
• 出版时间：September, 2013
• 年：2013
• 卷：45
• 期：7
• 页码：2692-2699
• 全文大小：1291 K

文摘

Background

Portal vein thrombosis (PVT) is a well-recognized complication of chronic liver disease with a prevalence ranging from 1 % to 16 % .

Materials and Methods

We performed a retrospective review of 447 consecutive patients who underwent liver transplantation (OLT) between October 2000 and December 2011 comparing 51 recipients with PVT (study group) with 399 without PVT (control group). The aim of this study was to determine the impact of pre-existent PVT on the surgical procedure, to identify specific preventable perioperative complications, and based on our studies and other works, to determine whether this group of patients are acceptable candidates for OLT.

Results

Among the 51 patients with PVT, 44 showed partial and 7 complete thrombosis. In 47 cases, we performed a thromboendovenectomy. There were six anastomoses at the confluence of the superior mesenteric vein (SMV) and one, with a venous graft interposition. In four complete thrombosis recipients we performed an extra-anatomic by pass?between the main trunk of the SMV and the donor portal vein. Compared with the control group, regarding preoperative characteristics, PVT patients were older at the?time of transplantation (m>Pm>?= .001) and had a higher use of TIPS (m>Pm>?= .02). The operative characteristics showed a longer warm ischemia time in the PVT group (46.9 ¡À 22.5 vs 39.3 ¡À 15 min; m>Pm>?= .004). There were significant differences in postoperative evaluations, nor in the complication rates. Overall survivals at 10 years were similar: 61.7 % versus 65.3 % ; (m>Pm>?= .9).

Conclusion

Although PVT was associated with greater operative complexity, it had no influence on postoperative complications or overall survival.