Chronic infection with Toxoplasma gondii induces death of submucosal enteric neurons and damage in the colonic mucosa of rats
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- 作者：Marcelo Biondaro Gó ; isa ; marcelobiondaro@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Catchia Hermes-Ulianab ; Maí ; sa Cristina Barreto Zagoa ; Jacqueline Nelisis Zanonia ; Aristeu Vieira da Silvac ; Marcí ; lio Hubner de Miranda-Netoa ; Eduardo José ; de Almeida Araú ; jod ; Dé ; bora de Mello Gonç ; ales Sant&rsquo ; Anaa
- 关键词：Mucins ; Submucosal plexus ; Vasoactive intestinal polypeptide ; Enteric nervous system ; Toxoplasmosis
- 刊名：Experimental Parasitology
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：164
- 期：Complete
- 页码：56-63
- 全文大小：1423 K
文摘
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Effects of genotype II Toxoplasma gondii on neuronal populations of the submucosal plexus in the rat proximal colon are described.
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Findings contribute to the establishment of an experimental model of this infectious disease and inflammatory bowel disease.
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ME-49 T. gondii is very aggressive to submucosal neurons in rat proximal colon, causing uncommon death of enteric neurons.