Investigating ego modules involved in TGFβ3-induced chondrogenesis in mesenchymal stem cells based on ego network

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• 作者：Jing-Guo Wu^a ; Qing-Wei Jia^a ; Yong Li^b ; Fei-Fei Cao^b ; Xi-Shan Zhang^a ; Cong Liu^c ; ^{congliu2016@163.com}
• 关键词：Mesenchymal stem cells ; TGFβ3 ; Gene expression ; Ego ; Module ; Network ; Pathway
• 刊名：Computational Biology and Chemistry
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：65
• 期：Complete
• 页码：16-20
• 全文大小：949 K
• 卷排序：65

文摘

A total of 15 ego genes were obtained from the DEN. Three ego modules (Module 3, Module 8 and Module 14) were identified, and all of them had statistical significances. Ego pathways, Cdc20:Phospho-APC/C mediated degradation of Cyclin A for Module 3, Mitohitic G1-G1/S phases for Module 8, and mRNA Splicing for Module 14.