Aggregation behavior of N-carboxyethylchitosan in aqueous solution: effects of pH, polymer concentration, and presence of a gemini surfactant

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• 作者：Baoliang Peng ; Yongliang Hao ; Hongmei Kang ; Xia Han ; Changjun Peng ; Honglai Liu
• 关键词：N-Carboxyethylchitosan ; Aggregation behavior ; Gemini surfactant
• 刊名：Carbohydrate Research
• 出版年：2010
• 出版时间：11 January 2010
• 年：2010
• 卷：345
• 期：1
• 页码：101-107
• 全文大小：529 K

文摘

A kind of biocompatible derivative of chitosan, N-carboxyethylchitosan (CECh) with a degree of substitution of 0.21 (DS 0.21) was synthesized by a Michael addition reaction. The aggregation behavior of CECh in aqueous solution under the effects of pH, polymer concentration, as well as a gemini surfactant, was investigated by turbidity, zeta potential, fluorescence spectroscopy, viscosity, and surface tension measurements. In the pH range of 3–11, the macroscopic phase separation of CECh from water occurs near the isoelectric point (IEP) due to the intense electrostatic attraction, and the intermolecular interaction at pH 4 is stronger than that at pH 10 over the whole CECh concentration region. The critical aggregation concentration (CAC) of CECh/12-n-12 (n = 3, 6) in basic media is determined to be between 0.0010 and 0.0015 mmol/L, and the length of the surfactant spacer is found to play an important role in the interaction of 12-n-12 with CECh.