Recent advances in microfluidic 3D cellular scaffolds for drug assays

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• 作者：Jing Wu^a ; ^{wujing@cugb.edu.cn} ; Qiushui Chen^b ; Wu Liu^b ; Ziyi He^b ; Jin-Ming Lin^b ; ^{jmlin@mail.tsinghua.edu.cn}
• 关键词：Microfluidic ; 3D cellular scaffold ; Drug assay ; Organs-on-chips ; Tissues-on-chips ; Nanodrug cytotoxicity analysis
• 刊名：TrAC Trends in Analytical Chemistry
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：87
• 期：Complete
• 页码：19-31
• 全文大小：2715 K
• 卷排序：87

文摘

Microfluidic 3D cell culture scaffolds serve as new platforms for cell-based drug assay. Recent fundamental development of microfluidic 3D cellular scaffolds was reviewed. The applications of these scaffolds in drug screening and nanodrug cytotoxicity analysis were highlighted.