Reversible escitalopram-induced hypothyroidism

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• 作者：Salih Saygin Eker ; Cengiz Akkaya ; Canan Ersoy ; Asli Sar ; ol ; Selcuk Kirli
• 关键词：Adverse event ; Escitalopram ; Hypothyroidism ; SSRI
• 刊名：General Hospital Psychiatry
• 出版年：2010
• 出版时间：September-October 2010
• 年：2010
• 卷：32
• 期：5
• 页码：559.e5-559.e7
• 全文大小：114 K

文摘

Some drugs can cause alterations in the concentration of thyroid hormones in blood even without clinical signs of dysfunction or pathology of the thyroid gland. Apart from the well-known relationship between depression and hypothalamic-pituitary-thyroid (HPT) axis, and the impact of selective serotonin reuptake inhibitors (SSRIs) on thyroid indices, hypothyroidism is a very rare adverse effect of SSRI treatment. However, the case presented here demonstrates that escitalopram may have the potential to induce hypothyroidism without any significant clinical signs and symptoms. Therefore, the possibility of SSRI-induced asymptomatic hypothyroidism presented here may help clinicians in this regard.