Cerebral autoregulation and white matter lesions in Parkinson's disease and multiple system atrophy
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- 作者：Elisabetta Indelicatoa ; b ; indelicato.elisabetta@gmail.it" class="auth_mail" title="E-mail the corresponding author ; Alessandra Fanciullia ; c ; Werner Poewec ; Angelo Antoninid ; Francesco E. Pontieria ; b ; Gregor K. Wenningc
- 关键词：Cerebral autoregulation ; Orthostatic hypotension ; Cerebral white matter lesions ; Multiple system atrophy ; Parkinson's disease
- 刊名：Parkinsonism & Related Disorders
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：21
- 期：12
- 页码：1393-1397
- 全文大小：1107 K
文摘
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Parkinson's disease and multiple system atrophy feature cardiovascular dysautonomia.
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The key feature is orthostatic hypotension, along with supine/nocturnal hypertension.
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Recent works link white matter lesions and dysautonomia in both diseases.
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Cerebral autoregulation is preserved in a range adapting to lower mean blood pressure.
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Pathologic adaptations may trigger cerebrovascular damage in dysautonomic patients.