Lowering Glucose to Prevent Adverse Cardiovascular Outcomes in a Critical Care Setting
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- 作者：Antonio Ceriello ; Stuart W. Zarich ; Roberto Testa
- 关键词：insulin ; impaired glucose tolerance ; diabetes ; myocardial infarction
- 刊名：Journal of the American College of Cardiology
- 出版年：2009
- 出版时间：3 February 2009
- 年：2009
- 卷：53
- 期：5, Supplement 1
- 页码：S9-S13
- 全文大小：203 K
文摘
High admission blood glucose levels after acute myocardial infarction are common and associated with an increased risk of death in patients with or without diabetes. Hyperglycemia is associated with altered myocardial blood flow and energetics and can lead to a pro-oxidative/proinflammatory state. The use of intensive insulin treatment has shown superior benefits in the treatment of hyperglycemia versus glucose-insulin-potassium infusion, particularly in critical care settings.