We retrospectively analyzed 9877 patients who underwent percutaneous coronary intervention (PCI) with drug-eluting stents (DES) and who were enrolled in the Korean Acute Myocardial Infarction Registry (KAMIR). They were divided into 2 groups, octogenarians (n = 1494) and non-octogenarians (n = 8383), in order to compare the incidence of 1-year all-cause death and 1-year major adverse cardiac events (MACE), where MACE included all-cause death, recurrent myocardial infarction, target vessel revascularization (TVR), target lesion revascularization (TLR), and coronary artery bypass grafting (CABG).
The clinical status was significantly inferior in octogenarians compared to non-octogenarians: Killip class ¡Ý II (34.8 % vs. 22.5 % , p < 0.001), multivessel disease (65.8 % vs. 53.7 % , p < 0.001). Rates of 1-year all-cause death were significantly higher in octogenarians than in non-octogenarians (22.3 % vs. 6.5 % , p < 0.001). However, the rates of 1-year recurrent myocardial infarction (1.3 % vs. 0.9 % , p = 0.68), TLR (2.4 % vs. 3.1 % , p = 0.69), TVR (3.6 % vs. 4.3 % , p = 0.96), and CABG (0.9 % vs. 0.9 % , p = 0.76) did not differ significantly between the 2 groups.
Octogenarian AMI patients have higher rates of mortality and MACE even in the DES era. According to KAMIR subgroup analysis, the TLR/TVR rates in octogenarians were comparable to those in non-octogenarian AMI patients.