Hemoglobin interacting proteins and implications of spectrin hemoglobin interaction
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- 作者：Avik Basu ; Abhijit Chakrabarti ; abhijit.chakrabarti@saha.ac.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：Chaperone ; Erythrocyte ; Hemoglobin ; Mass spectrometry ; Protein&ndash ; protein interaction ; Spectrin
- 刊名：Journal of Proteomics
- 出版年：2015
- 出版时间：14 October 2015
- 年：2015
- 卷：128
- 期：Complete
- 页码：469-475
- 全文大小：695 K
文摘
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We have analyzed interacting partners of Hemoglobin (Hb) inside erythrocyte.
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Hb interacts with cytosolic redox regulators, chaperones and metabolic enzymes.
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Various membrane skeleton proteins including spectrin also interact with Hb.
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Spectrin possibly acts as chaperone for free alpha globin chain at least in vitro.