Bacterial and viral co-infections complicating severe influenza: Incidence and impact among 507 U.S. patients, 2013-14
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22.5% of adult patients with H1N1 developed bacterial co-infection.

Staphylococcus aureus was the most common cause of co-infection.

Bacterial and viral co-infections were associated with death in bivariate.

Patients with a bacterial co-infection had greater use of resources.

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