Association of single nucleotide polymorphism with arsenic-induced skin lesions and genetic damage in exposed population of West Bengal, India
详细信息 查看全文
- 作者：Nandana Dasa ; Allan Girib ; 1 ; Sayan Chakrabortya ; Pritha Bhattacharjeeb ; 777.pritha@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Arsenic toxicity ; Drinking water ; Skin lesions ; Single nucleotide polymorphism ; Genetic damage
- 刊名：Mutation Research/Genetic Toxicology and Environmental Mutagenesis
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：809
- 期：Complete
- 页码：50-56
- 全文大小：1394 K
文摘
- •
C10orf32 G > A polymorphism (rs9527) is associated with increased risk toward the development of arsenic-induced skin lesions.
- •
The risk genotype is significantly associated with arsenic-induced genetic instability.
- •
C10orf32 SNP could be used as a biomarker for assessment of arsenic susceptibility.