Early childhood adversity potentiates the adverse association between prenatal organophosphate pesticide exposure and child IQ: The CHAMACOS cohort
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- 作者：Lauren J. Stein ; Robert B. Gunier ; Kim Harley ; Katherine Kogut ; Asa Bradman ; Brenda Eskenazi ; PhD ; eskenazi@berkeley.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Organophosphate pesticides ; Pesticides ; Early life adversity ; In utero exposures ; Child IQ
- 刊名：Neurotoxicology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：56
- 期：Complete
- 页码：180-187
- 全文大小：357 K
文摘
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Prenatal exposure to OPs was previously found to be adversely related to child IQ.
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We show that certain life stressors are negatively associated with children⿿s IQ.
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Prenatal OP exposure has stronger association with IQ in youth with more life stress.
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The types of stressors that interact with prenatal OP exposure vary by child sex.
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This is the first human study of interaction of pesticides and social stressors.