Evidence for an antihypertensive effect of a land snail (Helix aspersa) by-product hydrolysate - Identification of involved peptides
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- 作者：Benoit Cudenneca ; benoit.cudennec@univ-lille1.fr" class="auth_mail" title="E-mail the corresponding author ; Nicolas Violleb ; Gabrielle Chataigné ; a ; Pascal Drevetc ; Jean-Franç ; ois Bissonb ; Pascal Dhulstera ; Rozenn Ravalleca
- 关键词：ACE inhibitory peptides ; By-products upgrading ; Land snail ; SHR rats ; VW ; VY
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：22
- 期：Complete
- 页码：602-611
- 全文大小：852 K
文摘
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ACE inhibitory activity of SBH was characterised by an IC50 value of 23 µg⋅mL−1.
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Five of the identified peptides in the active fraction are well known ACE inhibitors.
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SBH stimulated intestinal cell metabolism and was not toxic for Wistar Rats.
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SBH significantly reduced systolic blood pressure in SHR rats.
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This snail by-product hydrolysate could be valorised as an antihypertensive ingredient.