Polymorphisms in Pfcrt and Pfmdr-1 genes after five years withdrawal of chloroquine for the treatment of Plasmodium falciparum malaria in West Bengal, India
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- 作者：Moytrey Chatterjeea ; moytreychatterjee@yahoo.in" class="auth_mail" title="E-mail the corresponding author ; Swagata Gangulyb ; swagatamedicine@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Pabitra Sahac ; pabitra.saha82@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Subhasish Kamal Guhae ; drskguha@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Nandita Basud ; stmkolkatadirector@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Dilip K. Beraa ; bera_dk.helminthology@yahoo.in" class="auth_mail" title="E-mail the corresponding author ; Ardhendu Kumar Majia ; maji_ardhendu@yahoo.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Chloroquine sensitivity ; Plasmodium falciparum ; Pfcrt ; Pfmdr-1 ; India
- 刊名：Infection, Genetics and Evolution
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：44
- 期：Complete
- 页码：281-285
- 全文大小：246 K
文摘
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Prevailing P. falciparum population of study area carries mutant K76T in pfcrt gene.
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All study isolates bearing SVMNT haplotype.
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Y184F mutation in pfmdr-1 gene was recorded in all isolates.
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No mutation at codon 86, 1246 of pfmdr-1 gene.