Nascent DNA Proteomics Reveals a Chromatin Remodeler Required for Topoisomerase I Loading at Replication Forks
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- 作者：Cyril Ribeyre1 ; cyril.ribeyre@igh.cnrs.fr" class="auth_mail" title="E-mail the corresponding author ; Ralph Zellweger2 ; Maeva Chauvin1 ; Nicole Bec3 ; Christian Larroque3 ; Massimo Lopes2 ; Angelos Constantinou1 ; angelos.constantinou@igh.cnrs.fr" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：12 April 2016
- 年：2016
- 卷：15
- 期：2
- 页码：300-309
- 全文大小：3080 K
文摘
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Proteins are identified at replication forks upon treatment with camptothecin
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BAZ1B facilitates Top1 function during DNA replication
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The suppression of BAZ1B protects against camptothecin-induced fork interference