MicroRNA-9 controls apoptosis of neurons by targeting monocyte chemotactic protein-induced protein 1 expression in rat acute spinal cord injury model
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- 作者：Yong Xua ; b ; 1 ; xuyong_rjh@163.com" class="auth_mail" title="E-mail the corresponding author ; Bao-Yan Anc ; 1 ; Xiao-Bing Xib ; Zhong-Wei Lia ; b ; Fei-Yue Lia ; b
- 关键词：Acute spinal cord injury ; MicroRNA-9 ; Monocyte chemotactic protein-induced protein 1
- 刊名：Brain Research Bulletin
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：121
- 期：Complete
- 页码：233-240
- 全文大小：2305 K
文摘
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MiR-9 expression in ASCI tissue was lower than that in normal spinal cord tissue.
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10">The reliability of our results is secured by in vitro experiment and rat model.
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15">MCPIP1 mRNA could be a negative target of miR-9 during ASCI.
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MiR-9 as an excellent therapeutic target for ASCI patients is well-elaborated.
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This topic contributes to early identification of intervention targets for ASCI.