Ifenprodil attenuates the acquisition and expression of methamphetamine-induced behavioral sensitization and activation of Ras-ERK1/2 cascade in the caudate putamen
详细信息 查看全文
- 作者：Lu Lia ; xjtutopll@163.com" class="auth_mail" title="E-mail the corresponding author ; Chuchu Qiaoc ; qcc0706@163.com" class="auth_mail" title="E-mail the corresponding author ; Gang Chena ; ronicechen@163.com" class="auth_mail" title="E-mail the corresponding author ; Hongyan Qiana ; 1414568425@qq.com" class="auth_mail" title="E-mail the corresponding author ; Ying Houd ; litao-hy@163.com" class="auth_mail" title="E-mail the corresponding author ; Tao Lia ; b ; litao050428@xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xinshe Liua ; b ; lxins@xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：AMPARs ; AMPA receptors ; CPu ; caudate putamen ; METH ; methamphetamine ; NAc ; nucleus accumbens ; NMDARs ; N-methyl-d-aspartate receptors ; PFc ; prefrontal cortex ; VTA ; ventral tegmental area
- 刊名：Neuroscience
- 出版年：2016
- 出版时间：29 October 2016
- 年：2016
- 卷：335
- 期：Complete
- 页码：20-29
- 全文大小：1975 K
文摘
- •
Ifenprodil attenuates the acquisition of METH-induced behavioral sensitization.
- •
Ifenprodil attenuates the expression of METH-induced behavioral sensitization.
- •
Chronic METH activates the Ras-ERK1/2-ΔFosB cascade in the CPu.
- •
Ifenprodil attenuates METH-induced activation of Ras-ERK1/2 cascade in the CPu.