Self-assembled nano-wire of an amphiphilic biodegradable oligosaccharide-based graft copolymer in water

详细信息    查看全文

• 作者：Xiong-Ying Qiu ; Ming-Wei Jiang ; Cheng-Gong Guo ; Yu-Jian He ; Cai-Qi Wang ; ^{wang-caiqi@gucas.ac.cn}
• 关键词：Maltoheptaose ; Poly(?-caprolactone) ; Self-assembly ; Graft copolymer ; Nano-wire
• 刊名：Carbohydrate Polymers
• 出版年：2012
• 出版时间：14 February, 2012
• 年：2012
• 卷：87
• 期：3
• 页码：2306-2312
• 全文大小：1042 K

文摘

A kind of amphiphilic biodegradable oligosaccharide-based graft copolymer was prepared and characterized by IR, H NMR and GPC, in which each hydrophobic poly(?-caprolactone) (PCL, average length ) was controlled grafted onto the 3-position hydroxyl group of the short and water soluble maltoheptaose (MH, DP = 7) backbone. The self-assembled structures in water of the amphiphilic MH-g-PCL₆ copolymer with a short main chain and controlled branched structure were investigated by transmission electron microscopy (TEM) and dynamic light scattering (DLC). The graft copolymer with a unique asymmetric structure self-assembled into wire-like micelles with average diameters of 76 nm. And the length of the nano-wire increased with increased initial copolymer concentration in dimethylformamide. Thus, a new route to form self-assembled nano-wires with different lengths and interesting biodegradable properties was developed using amphiphilic oligosaccharide-based graft copolymer in water. The possible formation mechanism of nano-wire micelles was also discussed.