Drug Repurposing: New Treatments for Zika Virus Infection?

详细信息    查看全文

• 作者：Feixiong Cheng¹ ; ² ; ^{fxcheng1985@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; James L. Murray³ ; Donald H. Rubin⁴ ; ⁵ ; ⁶
• 关键词：antiviral ; drug repurposing ; Zika virus ; mechanism-of-action
• 刊名：Trends in Molecular Medicine
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：22
• 期：11
• 页码：919-921
• 全文大小：894 K

文摘

To date, no antiviral agents have been approved for treating Zika virus (ZIKV) infection. Two recent drug-repurposing studies published in Cell Host & Microbe and Nature Medicine demonstrated that screening FDA-approved drugs for antiviral activity is a promising strategy for identifying therapeutics with novel activity against ZIKV infection.