Coculture of SCAPs and HUVECs yielded significantly longer tubule lengths.
Delayed addition of SCAPs to HUVECs resulted in longer-persisting vessel structure.
EphrinB2 phosphorylation started at 0.5 hours of coculture and peaked at 1 hour.
Enhanced migration of HUVECs by SCAPs could be inhibited by ephrinB2-Fc.
EphrinB2-Fc stabilized vascularlike structures compared to the control group.
EphrinB2 plays an important role in stabilization of vascularlike structures.