Synthesis and asymmetric catalytic activities of chiral organogallium and indium complexes with ephedrine derivatives as ligands. The crystal structure of [(1R, 2S)-(Me₂Ga-

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• 作者：Yuan ; Fang ; Zhu ; Chengjian ; Sun ; Jiangtao ; Liu ; Yongjiang ; Pan ; Yi
• 关键词：Organogallium ; Organoindium ; (&minus ; )-Ephedrine derivatives ; Crystal structure ; Asymmetric catalysis
• 刊名：Journal of Organometallic Chemistry
• 出版年：2003
• 出版时间：October 1, 2003
• 年：2003
• 卷：682
• 期：1-2
• 页码：102-107
• 全文大小：348 K

文摘

Reactions of trimethylgallium or trimethylindium with (1R, 2S)-(−)-ephedrine derivatives afford compounds [(1R, 2S)-(Me₂E-μ-OCH(C₆H₅)CH(CH₃)-μ-NRCH₃)]₂ [E=Ga, R=H (1), CH₃ (2), CH₂Ph (3); E=In, R=H (4), CH₃ (5), CH₂Ph (6)] in high yields. The resulting complexes 1–6 have been characterized by ¹H-NMR spectroscopy and elemental analysis. Structure of the compound 1 determined by single-crystal X-ray analysis shows a dimeric feature containing a standard parallelogram Ga₂O₂ core bridging through the oxygen atom of ephedrine group. The catalytic asymmetric isocyanosilylation of meso cyclohexene oxide with trimethylsilyl cyanide has been realized with complexes 1–6 as catalysts.