Electrochemical behavior of propranolol hydrochloride in neutral solution on platinum nanoparticles doped multi-walled carbon nanotubes modified glassy carbon electrode
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- 作者：Zhao Kun ; He Yi ; Zhu Chengyun ; Yuan Yue ; Zang Shuliang ; Zhang Yuyang
- 关键词：Electrochemistry ; Chemically modified electrode ; Platinum nanoparticles ; Multi-walled carbon nanotubes ; Propranolol hydrochloride
- 刊名：Electrochimica Acta
- 出版年：2012
- 出版时间：1 October, 2012
- 年：2012
- 卷：80
- 期：Complete
- 页码：405-412
- 全文大小：1323 K
文摘
Platinum nanoparticles (PtNPs) were used in combination with multi-walled carbon nanotubes (MWCNTs) with Nafion as the adhesives for fabricating sensitivity-enhanced electrochemical propranolol hydrochloride (PRO) sensor. The modifier, PtNPs doped MWCNTs (PtNPs/MWCNTs), was characterized by transmission electron microscopy (TEM) and electrochemical method which showed an excellent character for electrocatalytic oxidization of PRO. In addition, the experimental parameters such as pH values, the concentration of PtNPs/MWCNTs and the scan rate were optimized. Due to the fine characteristics of PtNPs/MWCNTs, a good linear relationship between the anodic peak current and PRO concentration in the range 6.76 ¡Á 10?7-3.8 ¡Á 10?5 M was observed. The detection limit of 8.45 ¡Á 10?8 M was achieved with the linear correlation coefficient R = 0.9965. The relative standard derivation was 2.74 % for 3.38 ¡Á 10?6 M PRO in 11 repeated determinations. This modified electrode showed excellent sensitivity and stability for the determination of PRO.