Robust fluorescence sensing platform for detection of CD44 cells based on graphene oxide/gold nanoparticles
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- 作者：Ha Young Jeong ; Seung Hun Baek ; Sung-Jin Chang ; Seon Ah Cheon ; Tae Jung Park ; tjpark@cau.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Graphene oxide/gold nanoparticles (GO/AuNPs) ; Fluorescence sensing ; Signal-to-background ratio enhancer ; Aptamer ; Hyaluronic acid binding domain of CD44
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2015
- 出版时间：1 November 2015
- 年：2015
- 卷：135
- 期：Complete
- 页码：309-315
- 全文大小：2066 K
文摘
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Fluorescence detection system to detect CD44 on the surface of cancer cells.
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TAMRA-labeled CD44 aptamer based on graphene oxide (GO)/gold nanoparticles (AuNPs).
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Specificity, sensitivity, selectivity, and ease of use.
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Detection limits of 1 × 101 CFU/mL.
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The fluorescence diagnosis using signal-to-background ratio enhancer to detect cancer cells.