S100A7: A rAMPing up AMP molecule in psoriasis

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• 作者：Fabio D&rsquo ; Amico ; ^{f.damico@unict.it}Author Vitae ; Evangelia Skarmoutsou ^{eskarmoutsou@gmail.com}Author Vitae ; Mariagrazia Granata ^{m_granata@live.it}Author Vitae ; Chiara Trovato ^{chiara.trovato@yahoo.it}Author Vitae ; Giulio Antonino Rossi ^{g.rossi8817@gmail.com}Author Vitae ; Maria Clorinda Mazzarino ^{clomazza@unict.it}Author Vitae
• 关键词：S100A7 ; Psoriasin ; Keratinocyte ; Psoriasis
• 刊名：Cytokine & Growth Factor Reviews
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：32
• 期：Complete
• 页码：97-104
• 全文大小：1276 K
• 卷排序：32

文摘

S100A7 (psoriasin) regulates many cell functions, including cell proliferation and differentiation. S100A7 production is dysregulated in many inflammatory contexts, such as in psoriasis. S100A7 is an emerging critical cytokine-like player in the psoriatic maintenance phase. Possible use of S100A7 as therapeutic target in psoriasis.