Immunization with Salmonella Enteritidis secreting mucosal adjuvant labile toxin confers protection against wild type challenge via augmentation of CD3⁺CD4⁺ T-cell proliferation and enhancement of IFN-γ, IL-6 and IL-10 expressions in chicken

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• 作者：Jonathan Lalsiamthara ; John Hwa Lee ; ^{johnhlee@jbnu.ac.kr}
• 关键词：Chickens ; Cytokines ; dmLT ; Flow cytometry ; RT-qPCR ; Salmonella Enteritidis
• 刊名：Vaccine
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：35
• 期：5
• 页码：767-773
• 全文大小：1039 K
• 卷排序：35

文摘

Salmonella Enteritidis JOL1641 secreting dmLT protects against virulent challenge. JOL1641 immunization enhances CD3+CD4+ T-cells proliferation. JOL1641 evoke in vitro splenocytes secretion of IFN-γ, IL-6, and IL-10 cytokines.