Solution Structure of Apoptotic BAX Oligomer: Oligomerization Likely Precedes Membrane Insertion
详细信息 查看全文
- 作者：Tai-Ching Sung1 ; Ching-Yu Li1 ; Yei-Chen Lai1 ; Chien-Lun Hung1 ; Orion Shih2 ; Yi-Qi Yeh2 ; U-Ser Jeng2 ; Yun-Wei Chiang1 ; ywchiang@mx.nthu.edu.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：Spin-label electron spin resonance ; Double electron-electron resonance ; Apoptosis
- 刊名：Structure
- 出版年：2015
- 出版时间：6 October 2015
- 年：2015
- 卷：23
- 期：10
- 页码：1878-1888
- 全文大小：3372 K
文摘
- •
ESR and SAXS reveal the solution structures of BAX oligomer
- •
BAX oligomer formation could occur prior to insertion into mitochondria
- •
An alternative pathway of the BAX-mediated apoptosis is suggested