Fatal leptospirosis and chikungunya co-infection: Do not forget leptospirosis during chikungunya outbreaks

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• 作者：Tu-Xuan Nhan^a ; ^{tnhan@ilm.pf" class="auth_mail" title="E-mail the corresponding author} ; Eric Bonnieux^b ; ^{eric.bonnieux@cht.pf" class="auth_mail" title="E-mail the corresponding author} ; Clarisse Rovery^c ; ^{crovery@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jean-Jacques De Pina^a ; ^{jdepina@ilm.pf" class="auth_mail" title="E-mail the corresponding author} ; Didier Musso^a ; ^{dmusso@ilm.pf" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Chikungunya ; Dengue ; French Polynesia ; Leptospirosis ; Outbreak
• 刊名：IDCases
• 出版年：2016
• 出版时间：2016
• 年：2016
• 卷：5
• 期：Complete
• 页码：12-14
• 全文大小：190 K

文摘

In endemic areas, leptospirosis can be missed by erroneous clinical or laboratory diagnosis of arboviroses or co-infections with arboviruses and an increase in mortality due to leptospirosis has already been reported during arboviruses outbreaks. During the French Polynesian chikungunya virus outbreak in 2014–2015, two leptospirosis and chikungunya co-infections were reported, one of which was fatal. Diagnosis of leptospiroses was delayed in the context of chikungunya outbreak. In the context of arbovirus outbreak, the risk of misdiagnosis of leptospirosis is maximum and clinicians should initiate early antibiotic therapy if leptospirosis is suspected. A delayed diagnosis of leptospirosis can be responsible for fatal outcome. Leptospirosis should be considered even if dengue or chikungunya virus infections are confirmed by reference molecular testing