Non-Hodgkin's lymphomas (NHLs) are the commonest type of lymphoma in childhood. Presentation as an emergency with rapidly increasing bulky disease and organ dysfunction is more commonly seen in this group of cancers than in others. Recognition of the potential pathology and appropriate management of complications through treatment results in very high cure rates for children with NHL. This update will review the main subtypes of NHL seen in children and consider the approaches to diagnosis and treatment.