刊名:Biochimica et Biophysica Acta (BBA) - Biomembranes
出版年:2017
出版时间:February 2017
年:2017
卷:1859
期:2
页码:218-227
全文大小:1487 K
卷排序:1859
文摘
GLIC-extracellular/ELIC transmembrane chimera exhibits impaired function ELIC-extracellular/GLIC transmembrane chimera (EG) gates open to an ELIC agonist EG gates open to protons at pH values below 4.5 Protons inhibit the EG agonist response 7 ≤ pH ≤ 4.5, but potentiate below pH 4.5 Thermal stability of chimeras is similar to that of the parent transmembrane domain