High resolution of racemic phenylalanine with dication imidazolium-based chiral ionic liquids in a solid-liquid two-phase system

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• 作者：Xiaoxia Huang ; Haoran Wu ; Zhixia Wang ; Yingjie Luo ; Hang Song ; ^{hangsong@vip.sina.com} ; ^{hangsong163@163.com} ; ^{hangsong@scu.edu.cn}
• 关键词：Solid-liquid two-phase system ; Phenylalanine ; Dication imidazolium-based chiral ionic liquids ; Resolution
• 刊名：Journal of Chromatography A
• 出版年：2017
• 出版时间：6 January 2017
• 年：2017
• 卷：1479
• 期：Complete
• 页码：48-54
• 全文大小：1418 K
• 卷排序：1479

文摘

A series of new dication imidazolium-based chiral ionic liquids were synthesized. Novel solid-liquid two-phase systems based on the chiral ionic liquids were developed. Excellent effect on enantiomeric separation of racemic phenylalanine was achieved with e.e. 99.2% and yield 85.2% for L-enantiomer in solid phase. The separation process is characteristic of no organic solvent, simple operation and fast separation process.