HHARI Is One HECT of a RING

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• 作者：Christopher W. Davies¹ ; Chittaranjan Das¹ ; ^{cdas@purdue.edu}
• 刊名：Structure
• 出版年：2013
• 出版时间：4 June, 2013
• 年：2013
• 卷：21
• 期：6
• 页码：872-874
• 全文大小：167 K

文摘

E3 ubiquitin ligases are the last of an enzyme trio that covalently modifies proteins with ubiquitin, facilitating various cellular functions. In this issue of Structure, Duda and colleagues provide the structural basis for the autoinhibited Ariadne-family of E3-ubiquitin ligases.