Total conversion of dichloromethane was reached at 450 °C over Al2O3 and PtAl2O3. Formation of by-products over PtTiO2 and PtCeO2 is smaller than over PtAl2O3. Dichloromethane oxidation is influenced by the nature and quantity of acid sites. By-products formation is influenced by acid sites and catalyst reducibility. Pt/Al2O3 showed good activity even after 55 h of stability test.