Suppressing effect of saikosaponin A, an active ingredient of Bupleurum falcatum, on chocolate self-administration and reinstatement of chocolate seeking in rats
Saikosaponin A is a major ingredient of the medicinal herb, Bupleurum falcatum. Saikosaponin A reduced self-administration of a chocolate-flavored beverage in rats. Saikosaponin A also reduced reinstatement of seeking for a chocolate-flavored beverage. These results extend the anti-addictive effect of saikosaponin A to a natural stimulus.