Serum levels of cholesterol, pregnenolone, DHEA, and their sulfate conjugates based on sex and pubertal stage in adolescents
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- 作者：Shin Hye Kima ; 1 ; Su Hyeon Leeb ; 1 ; Won-Yong Leec ; Jeongae Leeb ; Bong Chul Chungb ; Mi-Jung Parka ; pmj@paik.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Man Ho Choib ; mh_choi@kist.re.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Sulfotransferase ; Cholesterol ; Pregnenolone ; Dehydroepiandrosterone ; Adolescent
- 刊名：Clinica Chimica Acta
- 出版年：2016
- 出版时间：1 October 2016
- 年：2016
- 卷：461
- 期：Complete
- 页码：47-52
- 全文大小：309 K
文摘
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Altered free and sulfated serum steroids in adolescents were evaluated.
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Sulfotransferase, CYP11A1 and CYP17A were also calculated.
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Sulfotransferase activities were significantly higher in boys than in girls.
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The activity of CYP11A1 was increased along with pubertal development.
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Sexual dimorphism during pubertal changes was identified.