Huperzine A protects sepsis associated encephalopathy by promoting the deficient cholinergic nervous function
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- 作者：Sen-zhi Zhua ; b ; c ; Wei-ping Huangb ; Lin-qiang Huangb ; Yong-li Hanb ; Qian-peng Hana ; Gao-feng Zhub ; Miao-yun Wenb ; Yi-yu Dengb ; yiyudeng666@163.com" class="auth_mail" title="E-mail the corresponding author ; Hong-ke Zenga ; b ; 1 ; zenghongke@vip.163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Sepsis associated encephalopathy ; Huperzine A ; Choline acetyltransferase ; Muscarinic acetylcholine receptor 1 ; Acetylcholinesterase ; Acetylcholine
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：19 September 2016
- 年：2016
- 卷：631
- 期：Complete
- 页码：70-78
- 全文大小：2914 K
文摘
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The hippocampal cholinergic nervous system was dynamically evaluated in sepsis rats.
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The abnormal neuroinflammation associates with sepsis associated encephalopathy.
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The cholinergic nervous dysfunction is involved in sepsis associated encephalopathy.
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Huperzine A exerts a neuroprotective effect on sepsis associated encephalopathy.