The effect of coactivation of muscarinic and nicotinic acetylcholine receptors on LTD in the hippocampal CA1 network
详细信息 查看全文
- 作者：Eriko Sugisakia ; b ; e-sugisaki@eng.tamagawa.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Yasuhiro Fukushimab ; c ; fukushima@mw.kawasaki-m.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Satoshi Fujiid ; sfujii@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Yoshihiko Yamazakid ; yyamazak@med.id.yamagata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Takeshi Aiharaa ; b ; aihara@eng.tamagawa.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Acetylcholine ; Cholinergic ; Interneuron ; Muscarinic acetylcholine receptor ; Nicotinic acetylcholine receptor ; STDP
- 刊名：Brain Research
- 出版年：2016
- 出版时间：15 October 2016
- 年：2016
- 卷：1649
- 期：part_PA
- 页码：44-52
- 全文大小：1299 K
文摘
- •
LTD induced by the positive timing was shifted to LTP in the presence of eserine.
- •
LTD by negative timing was shifted toward potentiation as eserine increased.
- •
The mAChRs on pyramidal neuron and interneuron were more responsible for STDP.
- •
The nAChRs sensitively fine-tuned the STDP induction.