Acoustic Behavior of a Reactivated, Commercially Available Ultrasound Contrast Agent

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• 作者：Songita A. Choudhury ; BS^a ; Feng Xie ; MD^b ; Paul A. Dayton ; PhD^c ; Thomas R. Porter ; MD^a ; ^{trporter@unmc.edu}
• 关键词：Microbubbles ; Droplets ; Acoustic activation
• 刊名：Journal of the American Society of Echocardiography
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：30
• 期：2
• 页码：189-197
• 全文大小：2381 K
• 卷排序：30

文摘

A commercially available lipid-encapsulated perfluoropropane MB can be condensed into submicrometer droplets and reactivated with diagnostic ultrasound. The droplets range in size from 50 to 1,000 nm, and all size ranges can be activated with diagnostic ultrasound at MIs of ≥0.7. Targeted in vivo activation of the droplets produces myocardial contrast in real time at higher MIs.