Effectiveness of antiepileptic therapy in patients with PCDH19 mutations
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- 作者：Jan Lottea ; jan.lotte@web.de" class="auth_mail" title="E-mail the corresponding author ; Thomas Bastb ; Peter Borusiakc ; Antonietta Coppolad ; J. Helen Crossd ; Petia Dimovae ; Andras Fogarasif ; Irene Graneß ; g ; Renzo Guerrinih ; Helle Hjalgrimi ; Reinhard Keimerj ; Christian M. Korffk ; Gerhard Kurlemannl ; Steffen Leizm ; Michaela Linder-Luchtn ; Tobias Loddenkempero ; Christine Makowskip ; Christian Mü ; heq ; Joost Nicolair ; Marina Nikanorovai ; Simona Pellacanih ; Sunny Philips ; Susanne Ruft ; Ivá ; n Sá ; nchez Ferná ; ndezo ; Kurt Schlachteru ; Pasquale Strianov ; Biayna Sukhudyanw ; Deyana Valchevax ; R. Jeroen Vermeulenr ; Tanja Weisbrodj ; Bernd Wilkeny ; Philipp Wolfz ; Gerhard Klugera ; aa
- 关键词：PCDH19 mutation ; Epilepsy ; Antiepileptic drugs ; Treatment ; Long-term effectiveness
- 刊名：Seizure
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：35
- 期：Complete
- 页码：106-110
- 全文大小：459 K
文摘
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Bromide and clobazam turned out to be the most effective drugs after 3 and 12 months.
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Three-quarters of our patients were seizure-free for at least 3 months, half of them for one year and two even for over 10 years.
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Assessing the effectiveness of drugs is difficult because an age-dependent and spontaneous seizure remission must be considered.