Chronic Back Pain Is Associated With Decreased Prefrontal and Anterior Insular Gray Matter: Results From a Population-Based Cohort Study
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- 作者：Hans-Christian Fritz&lowast ; ; James H. McAuley&dagger ; ; &Dagger ; ; Katharina Wittfeld§ ; ; Katrin Hegenscheid¶ ; ; Carsten O. Schmidt&lowast ; &lowast ; ; Sö ; nke Langner¶ ; ; Martin Lotze&lowast ; ; martin.lotze@uni-greifswald.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Voxel-based morphometry ; gray matter volume ; chronic back pain
- 刊名：The Journal of Pain
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：17
- 期：1
- 页码：111-118
- 全文大小：1036 K
文摘
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This work is a cohort study on brain gray matter changes in chronic back pain (CBP) applying voxel-based morphometry.
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Patients with CBP showed decreased prefrontal and anterior insular gray matter.
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Pain intensity was associated with a decrease in prefrontal and anterior cingulate cortex gray matter.