Retromer Sets a Trap for Endosomal Cargo Sorting

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• 作者：Ludger Johannes¹ ; ^{ludger.johannes@curie.fr} ; Christian Wunder¹
• 刊名：Cell
• 出版年：2016
• 出版时间：1 December 2016
• 年：2016
• 卷：167
• 期：6
• 页码：1452-1454
• 全文大小：408 K
• 卷排序：167

文摘

Membrane trafficking from endosomes to the trans-Golgi network or the plasma membrane is driven by the retromer complex. Through structural analysis of the cargo-bound complex, Lucas et al. describe a mechanism by which endosomal membrane recruitment and cargo recognition are integrated through cooperative interactions between retromer subunits.