C-kit+ resident cardiac stem cells improve left ventricular fibrosis in pressure overload
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文摘

C-kit+ resident cardiac stem cells were intravenously infused after aortic ligation in mice.

Transplantation of stem cells induces the following effects in the pressure overloaded left ventricular myocardium:

Reduction of fibrosis and cardiomyocyte cross-sectional area

Increase of endothelial cells

Reduction of apoptosis and oxidative stress

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